Volume 51, Issue 12 p. 1133-1138
Free Access

Pruritus—itching for a cause and relief?

P. C. A. KAM

P. C. A. KAM

P.C.A. Kam, FRCA, FANZCA, FFARCSI, Senior Lecturer, K.H. Tan, MBBS , Provisional Fellow in Anaesthesia, Department of Anaesthesia, Royal Prince Alfred Hospital, Missenden Road, Camperdown, N.S.W. 2050, Australia.

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K. H. TAN

K. H. TAN

P.C.A. Kam, FRCA, FANZCA, FFARCSI, Senior Lecturer, K.H. Tan, MBBS , Provisional Fellow in Anaesthesia, Department of Anaesthesia, Royal Prince Alfred Hospital, Missenden Road, Camperdown, N.S.W. 2050, Australia.

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First published: December 1996
Citations: 59

Summary

The mechanisms of pruritus, an unpleasant irritation on the skin that provokes an urge to scratch, are reviewed. Whilst symptomatic treatment is only partially effective, antihistamines remain the first choice of treatment. However, recent novel treatment using opiate antagonists, propofol (subhypnotic doses) and serotonin antagonists offer attractive alternatives.